Selected Projects


Probing the role of sodium channels in painful neuropathies.

Neuropathic pain is a frequent feature of peripheral neuropathy adversely impacting patients’ quality of life and increasing health care costs. The PROPANE STUDY aims to address these issues through a solid clinical and genetic approach employing an innovative technological platform.

The main objectives are to resolve the genetic architecture of painful neuropathy achieving a stratification of high-risk neuropathic pain patients by novel biomarkers, to deepen understanding of underlying mechanisms and druggable targets and to identify new molecules tailored to potentially drug-responder patients and determine their effects in pre-clinical settings.

Consortium: 9 partners from 6 countries

Coordinator of the project: Fondazione IRCCS Istituto Neurologico Carlo Besta – Italy

Funding programme: FP7-HEALTH

Project start: October 2013

End date for the project: 30 September 2016

For more information go to the website